- Really cool paper from Haas/Trumpp/Velten labs
- Precise definitions of hematopoietic cells in the bone marrow based on surface marker expression and 462 mRNAs
- Useful for people who want to isolate cell types with FACS but also lots of good marker genes for using with scRNA-seq
- Found that the surface protein is only modestly affected by ageing but the majority of AML cells clustered away from the healthy differentiation trajectory > "Our data resource and bioinformatic advances enable the efficient identification and isolation of any molecularly defined cell state from blood and bone marrow while laying the grounds for reconciling flow cytometry and single-cell genomics data across human tissues."
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